da admin | Ott 8, 2025 | Scientific
Background: Despite the global burden of cocaine use, no pharmacological agent has received regulatory approval for the treatment of cocaine use disorder (CUD). This study aims to systematically evaluate efficacy and safety of topiramate, with a focus on its...
da admin | Ago 16, 2025 | Scientific
Background: Secular trends in adolescent alcohol and cannabis use in the general population have shown declines in both substances, but trends among high-risk youth placed in residential care are unclear. Understanding these differences could help address...
da admin | Ott 5, 2022 | Scientific
New psychoactive substances (NPS) are an issue of global concern posing a serious threat to the healthcare systems. Consumption of some NPS has been associated with toxic effects on the liver amongst others. However, data concerning their (cyto-)toxicity are usually...
da admin | Set 5, 2022 | Scientific
Background and objectives: Currently, safety pharmacological tests for the central nervous system depend on animal behavioral analysis. However, due to the subjectivity of behavioral analysis and differences between species, there is a limit to appropriate nervous...
da admin | Dic 20, 2021 | Scientific
Cocaine use disorder (CUD) is characterized by a compulsive search for cocaine. Several studies have shown that cocaine users exhibit cognitive deficits, including lack of inhibition and decision-making as well as brain volume and diffusion-based white-matter...
